Lab News

July 2025

Kayla and Connor are appointed to the Genetics T32 Training Grant for the 2025-26 academic year.

Chad and Anna are invited to speak at the Med13L Family Research Day Conference. 


June 2025

Kayla wins 1st place for her poster at the 50th Anniversary Genetics Student Retreat.

Anna and Kayla receive a travel grant from Uplifting Athletes. 


May 2025

Ismail Ademi, medical student, joins the Grueter Lab.

Kayla passes her comprehensive exam. 

Anna is invited to give a talk as a Marie Currie Speaker at College of Saint Mary. 


February 2025

Ella Riniker, an undergraduate student, joins the Grueter Lab. 


November 2024

Kayla wins first place for Best Trainee Presentation at the 50th Anniversary ACRC Symposium.

Anna wins first place for Best Postdoctoral Poster at the 50th Anniversary ACRC Symposium: A dynamical systems model for the total fission rate in DRP1 dependent mitochondrial fission.

Anna's paper on DRP1- dependent mitochondrial fission is published. 

A Dynamical System Model for the Total Fission Rate in DRP1-Dependent Mitochondrial Fission

Leinheiser AK, Mitchell CC, Rooke E, Strack S, Grueter CE. A dynamical systems model for the total fission rate in Drp1-dependent mitochondrial fission. PLoS Comput Biol. 2024 Nov 18;20(11):e1012596. doi: 10.1371/journal.pcbi.1012596. PMID: 39556606; PMCID: PMC11611272.


August 2024

Connor Kirk, a genetics PHD student, joins the Grueter Lab. 

Connor is awarded the Iowa Recruitment Fellowship from the Graduate College.


July 2024

Kayla is appointed to the Genetics T32 Training Grant for the 2024-25 academic year.

Anna is appointed to the Diabetes T32 Training Grant for the 2024-25 academic year. 


May 2024

Christopher Jun, medical student, joins the Grueter Lab.

Mariela Rosales, un undergraduate student, joins the Grueter Lab. 


August 2023

Dr. Anna Leinheiser joins the Grueter Lab. 

Kayla Henry, a genetics PHD student, joins the Grueter Lab.


May 2021

Eva's paper on mitral valve disease is published. 

Mining Metabolomics in Mitral Valve Disease

Scheibe EL, Grueter CE. Mining Metabolomics in Mitral Valve Disease. J Am Heart Assoc. 2021 May 4;10(9):e020726. doi: 10.1161/JAHA.121.020726. Epub 2021 Apr 23. PMID: 33890481; PMCID: PMC8200764.


April 2020

Jessica's paper on Cyclin C and mitochondrial dynamics is published. 

Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics

Ponce JM, Coen G, Spitler KM, Dragisic N, Martins I, Hinton A Jr, Mungai M, Tadinada SM, Zhang H, Oudit GY, Song LS, Li N, Sicinski P, Strack S, Abel ED, Mitchell C, Hall DD, Grueter CE. Stress-Induced Cyclin C Translocation Regulates Cardiac Mitochondrial Dynamics. J Am Heart Assoc. 2020 Apr 7;9(7):e014366. doi: 10.1161/JAHA.119.014366. Epub 2020 Apr 4. PMID: 32248761; PMCID: PMC7428645.


September 2019

Rachel's paper on gene expression is published.

Targeting Transcriptional Machinery to Inhibit Enhancer-Driven Gene Expression in Heart Failure

Minerath RA, Hall DD, Grueter CE. Targeting transcriptional machinery to inhibit enhancer-driven gene expression in heart failure. Heart Fail Rev. 2019 Sep;24(5):725-741. doi: 10.1007/s10741-019-09792-3. PMID: 30972522; PMCID: PMC6698214.


April 2019

Rachel's paper on Med 13 is published. 

Regulation of Cardiac Transcription by thyroid Hormone and Med 13 

Minerath RA, Dewey CM, Hall DD, Grueter CE. Regulation of cardiac transcription by thyroid hormone and Med13. J Mol Cell Cardiol. 2019 Apr;129:27-38. doi: 10.1016/j.yjmcc.2019.01.007. Epub 2019 Feb 12. PMID: 30769017; PMCID: PMC6510257.


February 2019

Duane's paper on Med1 and RNA Polymerase II is published. 

Disruption of Cardiac Med1 Inhibits RNA Polymerase II Promoter Occupancy and Promotes Chromatin Remodeling 

Hall DD, Spitler KM, Grueter CE. Disruption of cardiac Med1 inhibits RNA polymerase II promoter occupancy and promotes chromatin remodeling. Am J Physiol Heart Circ Physiol. 2019 Feb 1;316(2):H314-H325. doi: 10.1152/ajpheart.00580.2018. Epub 2018 Nov 21. PMID: 30461303; PMCID: PMC6397381.


October 2017

Rachel wins 3rd Place for the Best Trainee Poster Presentation at University of Iowa Department of Internal Medicine Research Day
Her Poster was :"CDK8 activity-dependent regulation of heart disease"


September 2017

Colleen wins Postdoctoral category of the ‘A Minute to Win It’ Poster Competition during the 22nd Annual Meeting of the Iowa Physiological Society.


August 2017

Duane's paper on CDK8 in the heart is published.
Ectopic expression of Cdk8 induces eccentric hypertrophy and heart failure.
Hall DD, Ponce JM, Chen B, Spitler KM, Alexia A, Oudit GY, Song LS, Grueter CE. JCI Insight. 2017 Aug 3;2(15). pii: 92476. doi: 10.1172/jci.insight.92476.
Read more at The Scientist


July 2017

Katie wins 2nd place in the Papajohn Biomedical Institute best paper competition for her paper: Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming.


April 2017

Katie wins Travel award from ScienceImpact to attend Experimental Biology 2017

Colleen is invited to give a talk at the FOEDRC Research Day
She presents "Med12 is an essential, early regulator of adipogenesis"


February 2017

Katie's paper on Med1 is published
Cardiac Med1 deletion promotes early lethality, cardiac remodeling, and transcriptional reprogramming.
Spitler KM, Ponce JM, Oudit GY, Hall DD, Grueter CE. Am J Physiol Heart Circ Physiol. 2017 Apr 1;312(4):H768-H780. doi: 10.1152/ajpheart.00728.2016. Epub 2017 Feb 3.


July 2016

Jessica wins 1st Place for the Best Trainee Poster Presentation at University of Iowa Department of Internal Medicine Research Day
Her Poster was :"Dual Roles of Cyclin C in Cardiovascular Disease"


September 2015

Jessica is awarded the Sloan Center Mini Grant


November 2015

Colleen's review of secreted factors as biomarkers is published
Cardiac-Secreted Factors as Peripheral Metabolic Regulators and Potential Disease Biomarkers.
Dewey CM, Spitler KM, Ponce JM, Hall DD, Grueter CE. J Am Heart Assoc. 2016 May 31;5(6). pii: e003101. doi: 10.1161/JAHA.115.003101. No abstract available.


January 2015

Jessica Ponce joins the lab as a graduate student.
Jessica plans to study the role of Cyclin C in the cardiovascular system.


September 2014

Dr. Colleen Dewey joins the lab as a postdoctoral fellow.
Colleen intends to investigate the involvement of the Mediator complex in metabolic disease.


June 2014

Ines Martin joins the lab.
Ines will focus on cardiovascular surgeries to provide critical models of stress for the lab.


April 2014

Funding awarded to Dr. Katie Spitler, NIH T32 Postdoctoral Fellowship.
Title: MED 13 regulates cardiac energetics in response to obesity.


March 2014

Dr. Katie Spitler joins the lab as a postdoctoral fellow.
Katie’s research will encompass MED13 and MED1 and there role in cardiac function.


January 2014

New graduate student, Rachael Minerath, has joined the lab.
Rachael’s work will be focused on the function of CDK19 in the heart under normal and stress conditions.


December 2013

Dr. Duane Hall joins the label as a research professor.
Duane intends to focus his efforts on eliciting the role of CDK8 in cardiac function.

 


January 2013

Dr. Chad Grueter starts the lab at the University of Iowa – Department of Internal Medicine.